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QIAGEN Reports Strong Fourth Quarter and Fiscal 2009 Results
GlobeNewswire
2010-02-08

              Fiscal 2009 Net Sales Exceed $1 Billion

VENLO, Netherlands, Feb. 8, 2010 (GLOBE NEWSWIRE) -- QIAGEN N.V.
(Nasdaq:QGEN) (Frankfurt:QIA) today announced the results of operations
for the fourth quarter and the fiscal year ended December 31, 2009.

The reported net sales for the fourth quarter 2009 exceeded the
guidance and reported net sales and adjusted earnings per share for
fiscal year 2009 were at the high end of company's expectations
provided by the Company on November 9, 2009. Reported net sales for
fiscal 2009 exceeded US$1 billion for the first time in the Company's
history.

Fourth Quarter 2009 Results


                                                          
  QIAGEN's Fourth Quarter 2009                            
  ---------------------------------  -----  -----  ------ 
                                                          
  in US$ millions, except per share   Q4     Q4           
   information                        2009   2008  Growth 
  ---------------------------------  -----  -----  ------ 
  Net sales                          289.1  237.2     22% 
  Net sales at constant exchange                          
   rates                             272.1  237.2     15% 
  Operating income, adjusted          83.4   66.6     25% 
  Net income, adjusted                57.6   43.7     32% 
                                                          
  EPS, adjusted (US$)                 0.24   0.22      9% 
  ---------------------------------  -----  -----  ------ 
                                                          
  For information on the adjusted figures, please refer   
   to the reconciliation table                            
  accompanying this release.                              



The Company reported that consolidated net sales for its fourth quarter
2009 increased 22% to $289.1 million from $237.2 million in the same
quarter of 2008. Excluding the favorable impact from foreign currency
exchange rates, net sales for the fourth quarter 2009 would have
increased 15% from the fourth quarter 2008. Reported operating income
for the quarter increased 6% to $42.9 million from $40.4 million in the
same quarter of 2008, and net income for the quarter increased 80% to
$44.5 million from $24.7 million in the same quarter of 2008. Diluted
earnings per share for the fourth quarter increased 50% to $0.18 in
2009 (based on 241.0 million weighted average shares and share
equivalents outstanding) from $0.12 in 2008 (based on 202.0 million
weighted average shares and share equivalents outstanding).

On an adjusted basis, fourth quarter operating income increased 25% to
$83.4 million in 2009 from $66.6 million in 2008, and fourth quarter
2009 adjusted net income increased 32% to $57.6 million from $43.7
million in 2008. Adjusted diluted earnings per share increased to $0.24
in the fourth quarter 2009 from $0.22 in 2008.

Fiscal Year 2009 Results


                                                                
                                                       
  QIAGEN's Fiscal Year 2009                  
  -------------------------------------  -------  -----  ------ 
                                                                
  in US$ millions, except per share        12M     12M          
   information                            2009     2008  Growth 
  -------------------------------------  -------  -----  ------ 
  Net sales                              1,009.8  893.0     13% 
  Net sales at constant exchange rates   1,038.6  893.0     16% 
  Operating income, adj.                   296.1  252.7     17% 
  Net income, adj.                         199.6  163.3     22% 
                                                                
  EPS, adj. (US$)                           0.93   0.80     16% 
  -------------------------------------  -------  -----  ------ 
                                                                
  For information on the adjusted figures, please refer to the  
   reconciliation table                                         
                                                          
  accompanying this release.                            



For the year ended December 31, 2009, net sales increased 13% to
$1,009.8 million compared to $893.0 million in 2008. Excluding the
unfavorable impact from foreign currency exchange rates, net sales for
the fiscal year 2009 would have increased 16%. Operating income as
reported for fiscal 2009 increased 24% to $180.2 million from $145.7
million in 2008. Net income increased 55% to $137.8 million from $89.0
million in 2008, and diluted earnings per share increased 45% to $0.64
in 2009 (based on 213.6 million weighted average shares and share
equivalents outstanding) from $0.44 in 2008 (based on 204.3 million
weighted average shares and share equivalents outstanding).

On an adjusted basis, operating income for the year ended December 31,
2009 increased 17% to $296.1 million in 2009 from $252.7 million in
2008, and adjusted net income increased 22% to $199.6 million from
$163.3 million. Adjusted diluted earnings per share in fiscal 2009
increased 16% to $0.93 per share from $0.80 per share in 2008.

QIAGEN's fourth quarter and fiscal year 2009 results include the
results of operations from the Company's recent acquisitions, the most
significant of which were SABiosciences Corporation, acquired in
December 2009, DxS Ltd., acquired in September 2009, and Corbett Life
Sciences, acquired in July 2008. Reconciliations of reported results
determined in accordance with generally accepted accounting principles
(GAAP) to adjusted results are included in the tables accompanying this
release.

"2009 was a very successful year for QIAGEN," said Peer Schatz,
QIAGEN's Chief Executive Officer. "Net sales and adjusted net income
demonstrated significant growth. Net sales grew 22% - significantly
faster than the overall market growth. Strong growth in net sales and
adjusted net income as well as an organic growth rate of 13% define the
most successful year in the company's history and drove revenues to
surpass the $1 billion mark. The solid foundation of innovation-driven,
organic growth also allows us to plan for strong growth in 2010 and
beyond.

"The largest revenue share we recorded for fiscal 2009 was in sales to
customers in molecular diagnostics (approximately 47% of total
revenues) followed by sales to customers in academia (approximately 26%
of total revenues), in pharma (approximately 21% of total revenues) and
in applied testing (approximately 6% of total revenues). Growth of our
sales to customers in molecular diagnostics was fueled by strong sales
of our profiling solutions (including our influenza and other
infectious disease assays) as well as products addressing prevention
(such as HPV screening and genotyping) and personalized healthcare
testing. Sales to customers in the pharmaceutical and biotech industry
conducting clinical development continued to experience solid growth
during the fourth quarter, academic research markets continued to
perform solidly and we are looking forward to the effect of the
stimulus programs which are expected for 2010 and into 2011.

"Our acquisition strategy remains focused, consistent and
value-creating, providing complementary technologies, new commercial
capabilities and geographic reach. For example, during 2009 we further
strengthened our strong content engine for research and molecular
diagnostics assays. In December 2009 we acquired SABiosciences and
added a portfolio of PCR-based, pathway-focused panels that represent
highly efficient solutions for pathway- and disease-biomarker discovery
and development and diagnostics development. The acquisition of DxS
Ltd. in September 2009 combined two leadership positions in companion
diagnostics to create a very powerful leader in a transformational area
of healthcare: personalized healthcare.

"In addition we formed a very promising position in point of need
testing. The acquisition of ESE GmbH in January 2010 added to QIAGEN's
instrumentation platform a portable, battery operated, "ultra-fast time
to result", analysis system. This platform can run QIAGEN assay
technologies in formats suitable for point of need testing in
healthcare and applied testing (e.g. veterinary, food, environmental,
biodefense testing), and in all other settings, where a laboratory
infrastructure is not accessible and low-throughput molecular testing
and fast turnaround is required.

"All three transactions contribute to key elements of our strategy to
lead in molecular diagnostics-based prevention, profiling, personalized
healthcare and point of need testing. With different platform
technologies that address all needs in terms of throughput, flexibility
in assay technologies, convenience in handling and efficiency in
performance, an industry leading assays portfolio and a pipeline that
provides us with an ongoing stream of new assays to launch, we are
excellently positioned not only to participate from but also to shape
current and future trends in molecular based testing and life science
research."

"QIAGEN experienced a successful fiscal year 2009 with reported
revenues and adjusted earnings per share at the high end of our
expectations," said Roland Sackers, QIAGEN's Chief Financial Officer.
"Assuming constant exchange rates for both fiscal years revenue growth
was 16% and was fueled by a strong organic growth of 13%, adjusted for
the divesture of certain assets related to our activities in HLA
diagnostics (transplantation diagnostics) in July 2009.

Our consumable products portfolio contributed 10% growth (13% at
constant exchange rates) in fiscal year 2009 and our sales of
instrumentation products recorded a growth rate of 37% (42% at constant
exchange rates). Net sales in the Americas for fiscal year 2009
represented approximately 49% of our overall business and recorded a
growth rate of 10% (12% at constant exchange rates) and European sales,
which represent approximately 36% of our revenues, showed a growth rate
of 11% (19% at constant exchange rates). Net sales in Asia remained
strong, showing a growth rate of 39% (36% at constant exchange rates)."

Fiscal Year 2010 Guidance

Based on foreign currency exchange rates as of January 31, 2010, QIAGEN
expects revenues between $1,120 and $1,170 million in 2010 with a
growth rate of 11% to 16% when compared to 2009 and adjusted diluted
earnings per share between $0.90 and $0.96 including a diluting effect
of $0.02 following the DxS acquisition in September 2009. Based on
foreign currency exchange rates as of November 9, 2009 (the date of the
Company's third quarter 2009 earnings conference call), revenue
guidance for 2010 would have been approximately $35 million higher.

QIAGEN -- Sample and Assay Technologies Highlights


  --  QIAGEN established the QIAGENcares program to support regions in need
      for effective diagnostic testing solutions and announced the first two
      programs under this Corporate Social Responsibility program:





  --  QIAGEN and the Chittaranjan National Cancer Institute (CNCI) formed a
      collaboration to establish the first large-scale cervical cancer
      screening program for women in Kolkata, India. The initiative will be
      conducted over 5 years and is expected to reach 50,000 women.
  --  QIAGEN agreed to donate one million HPV tests over the run of this
      cancer screening program.





  --  QIAGEN entered into an agreement to supply molecular sample and assay
      technologies for a new national, PCR-based blood screening program for
      HIV and Hepatitis C (HCV) in Brazil. QIAGEN will provide Bio-Manguinhos,
      the main provider of vaccines and diagnostics to the Brazilian Ministry
      of Health, with a significant volume of molecular testing solutions --
      sample and assay technologies, related instrumentation, operational
      know-how and training. The agreement is expected to run for five years
      and contains options for subsequent extensions.
  --  QIAGEN significantly expanded its strategic position in molecular
      diagnostics:





  --  QIAGEN acquired Explera s.r.l., a leading supplier in molecular
      diagnostics and personalized medicine in Italy. With this acquisition
      QIAGEN is doubling the size of its molecular diagnostics sales channel
      in Italy and is adding several activities in the area of personalized
      medicine and access to a suite of CE-IVD pyrosequencing assays.
  --  QIAGEN acquired DxS Ltd., a developer and manufacturer of companion
      diagnostic products (CDx) for Personalized Healthcare (PHC). With this
      acquisition, QIAGEN has added to its own activities in CDx and taken a
      strong leadership position in the new era of PHC.
  --  QIAGEN acquired SABiosciences. This transaction added to QIAGEN's
      product offering a leading portfolio of PCR-based, disease and
      pathway-based panels that play key roles in biomedical research and the
      development of future drugs and diagnostics.
  --  QIAGEN acquired ESE GmbH, a developer and manufacturer of portable,
      battery operated, "ultra-fast time to result", multiplex UV and
      fluorescence optical measurement devices which enable low-throughput
      molecular testing in practices, emergency rooms, remote field areas, and
      other settings where a laboratory infrastructure is not accessible and
      fast turnaround is required.





  --  QIAGEN launched 79 new products in the area of Sample & Assay
      Technologies including the PAXgene Blood miRNA kit for use in cancer,
      biomarker and miRNA research and the QIAamp Circulating Nucleic Acid kit
      for sample preparation in prenatal or other circulating nucleic acid
      research. In addition QIAGEN launched a number of assay technologies
      including two multiplexed, PCR-based CE-marked digene HPV Genotyping
      Tests, a next generation CE marked mutation profiling KRAS test as well
      as a BRAF test for use in cancer treatments and assay technologies for
      epigenetic methylation analysis based on pyrosequencing technology.
  --  QIAGEN and Pfizer entered into an agreement to develop a companion
      diagnostic assay for PF-04948568 (CDX-110), an immunotherapy vaccine in
      development for the treatment of glioblastoma multiforme (GBM).
      Glioblastoma multiforme is the most common malignant primary brain tumor
      in adults and occurs in around 25,000 patients worldwide each year.
      Pfizer's investigational drug PF-04948568 (CDX-110) is a peptide vaccine
      which targets the tumor-specific Epidermal Growth Factor Receptor
      variant III (EGFRvIII), a mutated form of the epidermal growth factor
      receptor that is only present in cancer cells and occurs in 25-40
      percent of GBM tumors. The QIAGEN assay is designed to identify those
      patients whose tumors express the EGFRvIII mutation, allowing for the
      possibility of more targeted and personalized treatment.
  --  QIAGEN acquired a global and exclusive license for biomarker PI3K from
      John Hopkins University and intends to develop PCR and real time-PCR
      assays for companion diagnostic use with certain cancer treatments. A
      number of studies suggest that mutations in the PI3K oncogene are
      indicative for successful antibody treatment of patients suffering from
      lung, breast and other cancers. The license includes all countries and
      allows QIAGEN to enter partnerships with pharmaceutical companies to
      develop and market tests for new cancer drug candidates.




Conference Call and Webcast Details

Detailed information on QIAGEN's business and financial performance
will be presented during its conference call on February 9, 2010 at
9:30am ET. The corresponding presentation slides will be available for
download on the Company's website at
www.qiagen.com/goto/ConferenceCall. A webcast of the conference call
will also be available at www.qiagen.com/goto/ConferenceCall.

Use of Adjusted Results

QIAGEN has regularly reported adjusted results to give additional
insight into its financial performance as well as considered results on
a constant currencies basis. Adjusted results should be considered in
addition to the reported results prepared in accordance with generally
accepted accounting principles, but should not be considered as a
substitute. The Company believes certain items should be excluded from
adjusted results when they are outside of its ongoing core operations,
vary significantly from period to period, or affect the comparability
of results with the Company's competitors and its own prior periods.
Reconciliations of reported results to adjusted results are included in
the tables accompanying this release.

About QIAGEN

QIAGEN N.V., a Netherlands holding company, is the leading global
provider of sample and assay technologies. Sample technologies are used
to isolate and process DNA, RNA and proteins from biological samples
such as blood or tissue. Assay technologies are used to make these
isolated biomolecules visible. QIAGEN has developed and markets more
than 500 sample and assay products as well as automated solutions for
such consumables. The Company provides its products to molecular
diagnostics laboratories, academic researchers, pharmaceutical and
biotechnology companies, and applied testing customers for purposes
such as forensics, animal or food testing and pharmaceutical process
control. QIAGEN's assay technologies include one of the broadest panels
of molecular diagnostic tests available worldwide. This panel includes
the first FDA-approved test for human papillomavirus (HPV), the primary
cause of cervical cancer. QIAGEN employs nearly 3,500 people in over 30
locations worldwide. Further information about QIAGEN can be found at
http://www.qiagen.com/.

The QIAGEN N.V. logo is available at
http://www.globenewswire.com/newsroom/prs/?pkgid=3692

Certain of the statements contained in this news release may be
considered forward-looking statements within the meaning of Section 27A
of the U.S. Securities Act of 1933, as amended, and Section 21E of the
U.S. Securities Exchange Act of 1934, as amended. To the extent that
any of the statements contained herein relating to QIAGEN's products,
markets, strategy or operating results, including without limitation
expected operating results, are forward-looking, such statements are
based on current expectations and assumptions that involve a number of
uncertainties and risks. Such uncertainties and risks include, but are
not limited to, risks associated with management of growth and
international operations (including the effects of currency
fluctuations, regulatory processes and dependence on logistics),
variability of operating results and allocations between business
segments, the commercial development of the applied testing markets,
personal healthcare markets, clinical research markets and proteomics
markets, women's health/HPV testing markets, nucleic acid-based
molecular diagnostics market, and genetic vaccination and gene therapy
markets, changing relationships with customers, suppliers and strategic
partners, competition, rapid or unexpected changes in technologies,
fluctuations in demand for QIAGEN's products (including fluctuations
due to general economic conditions, the level and timing of customers'
funding, budgets, and other factors), our ability to obtain regulatory
approval of our infectious disease panels, difficulties in successfully
adapting QIAGEN's products to integrated solutions and producing such
products, the ability of QIAGEN to identify and develop new products
and to differentiate and protect its products from competitors'
products, market acceptance of QIAGEN's new products and the
integration of acquired technologies and businesses. For further
information, refer to the discussions in reports that QIAGEN has filed
with, or furnished to, the U.S. Securities and Exchange Commission
(SEC).


  QIAGEN N.V.                                          
  CONDENSED CONSOLIDATED STATEMENTS OF INCOME          
  (unaudited)                                          
                                                       
                                       Three months    
  (in thousands, except per                            
   share data)                      ended December 31, 
                                    ------------------ 
                                                       
                                      2009      2008   
                                    --------  -------- 
  Net sales                         $289,077  $237,182 
                                                       
   Cost of sales                     100,965    79,731 
                                    --------  -------- 
                                                       
  Gross profit                       188,112   157,451 
                                    --------  -------- 
                                                       
  Operating expenses:                                  
   Research and development           30,560    28,049 
   Sales and marketing                68,957    59,662 
   General and administrative,                         
    integration and other             39,723    25,265 
   Acquisition-related                                 
    intangible amortization            5,933     3,884 
   Purchased in-process                                
    research and development              --       155 
                                    --------  -------- 
                                                       
  Total operating expenses           145,173   117,015 
                                    --------  -------- 
                                                       
                                                       
  Income from operations              42,939    40,436 
                                    --------  -------- 
                                                       
  Other income (expense):                              
   Interest income                       980     2,121 
   Interest expense                  (7,504)   (8,695) 
                                                       
   Other income, net                  12,996     2,311 
                                    --------  -------- 
                                                       
  Total other income (expense)         6,472   (4,263) 
                                    --------  -------- 
                                                       
  Income before provision for                          
   income taxes                       49,411    36,173 
                                                       
  Provision for income taxes           4,947    11,490 
                                    --------  -------- 
  Net income attributable to                           
   QIAGEN N.V.                       $44,464   $24,683 
                                    ========  ======== 
                                                       
   Weighted average number of                          
    diluted common shares            241,018   202,039 
                                                       
   Diluted net income                                  
    attributable to QIAGEN N.V.                        
    per common share                   $0.18     $0.12 
                                                       
   Diluted net income attributable                     
    to QIAGEN N.V. per common                          
    share, adjusted                    $0.24     $0.22 






                                    





  QIAGEN N.V.                                         
  CONDENSED CONSOLIDATED STATEMENTS OF INCOME         
  (unaudited)                                         
                                                      
                                    Twelve months     
  (in thousands, except per                           
   share data)                    ended December 31,  
                                 -------------------- 
                                                      
                                    2009       2008   
                                 ----------  -------- 
  Net sales                      $1,009,825  $892,975 
                                                      
   Cost of sales                    342,752   293,285 
                                 ----------  -------- 
                                                      
  Gross profit                      667,073   599,690 
                                 ----------  -------- 
                                                      
  Operating expenses:                                 
   Research and development         107,900    97,331 
   Sales and marketing              244,814   227,408 
   General and administrative,                        
    integration and other           115,933   113,936 
   Acquisition-related                                
    intangible amortization          18,221    14,368 
   Purchased in-process                               
    research and development             --       985 
                                 ----------  -------- 
                                                      
  Total operating expenses          486,868   454,028 
                                 ----------  -------- 
                                                      
                                                      
  Income from operations            180,205   145,662 
                                 ----------  -------- 
                                                      
  Other income (expense):                             
   Interest income                    3,522     9,511 
   Interest expense                (29,641)  (37,527) 
                                                      
   Other income, net                 18,244     1,640 
                                 ----------  -------- 
                                                      
  Total other expense               (7,875)  (26,376) 
                                 ----------  -------- 
                                                      
  Income before provision for                         
   income taxes and                                   
   noncontrolling interest          172,330   119,286 
                                                      
  Provision for income taxes         34,563    29,762 
                                 ----------  -------- 
                                                      
  Net income                        137,767    89,524 
                                 ----------  -------- 
                                                      
  Less: Noncontrolling interest          --       491 
                                 ----------  -------- 
  Net income attributable to                          
   QIAGEN N.V.                     $137,767   $89,033 
                                 ==========  ======== 
                                                      
   Weighted average number of                         
    diluted common shares           213,612   204,259 
                                                      
   Diluted net income                                 
    attributable to QIAGEN N.V.                       
    per common share                  $0.64     $0.44 
                                                      
   Diluted net income                                 
    attributable to QIAGEN N.V.                       
    per common share, adjusted        $0.93     $0.80 








  QIAGEN N.V.                                           
  CONDENSED CONSOLIDATED BALANCE SHEETS                 
                                                        
                                                        
   (in thousands, except par     December     December  
    value)                          31,         31,     
                                                        
                                   2009         2008    
                                -----------  ---------- 
  Assets                        (unaudited)             
                                                        
  Current Assets:                                       
   Cash and cash equivalents       $825,557    $333,313 
   Short-term investments            40,000          -- 
   Accounts receivable, net         193,737     158,440 
   Income taxes receivable           12,907      14,441 
   Inventories, net                 130,851     108,563 
   Prepaid expenses and other        96,893      61,424 
                                                        
   Deferred income taxes             33,525      27,374 
                                -----------  ---------- 
                                                        
     Total current assets         1,333,470     703,555 
                                -----------  ---------- 
                                                        
  Long-Term Assets:                                     
   Property, plant and                                  
    equipment, net                  317,467     289,672 
   Goodwill                       1,337,064   1,152,105 
   Intangible assets, net           752,296     640,309 
   Deferred income taxes             26,387      73,766 
                                                        
   Other assets                      29,780      25,916 
                                -----------  ---------- 
                                                        
     Total long-term assets       2,462,994   2,181,768 
                                -----------  ---------- 
                                                        
                                                        
                                -----------  ---------- 
                                                        
    Total assets                 $3,796,464  $2,885,323 
                                ===========  ========== 
                                                        
  Liabilities and                                       
   Shareholders' Equity                                 
                                                        
  Current Liabilities:                                  
   Accounts payable                 $43,775     $48,836 
   Accrued and other                                    
    liabilities                     248,699     163,513 
   Income taxes payable              10,727      14,288 
   Current portion of                                   
    long-term debt                   50,000      25,000 
   Current portion of capital                           
    lease obligations                 3,417       2,984 
                                                        
   Deferred income taxes             18,912       7,754 
                                -----------  ---------- 
                                                        
     Total current liabilities      375,530     262,375 
                                -----------  ---------- 
                                                        
  Long-Term Liabilities:                                
   Long-term debt, net of                               
    current portion                 870,000     920,000 
   Capital lease obligations,                           
    net of current portion           27,554      29,718 
   Deferred income taxes            212,690     212,589 
                                                        
   Other                             19,521       6,797 
                                -----------  ---------- 
     Total long-term                                    
      liabilities                 1,129,765   1,169,104 
                                -----------  ---------- 
                                                        
  Shareholders' Equity:                                 
   Common shares, EUR .01 par                           
    value:                                              
    Authorized---410,000                                
     shares                                             
    Issued and                                          
     outstanding---232,074                              
     shares in 2009 and                                 
     197,839 shares in 2008           2,711       2,212 
    Additional paid-in-capital    1,622,733     958,665 
    Retained earnings               615,579     477,812 
    Accumulated other                                   
     comprehensive income            50,146      15,155 
                                -----------  ---------- 
     Total QIAGEN N.V.                                  
      shareholders' equity        2,291,169   1,453,844 
                                -----------  ---------- 
                                                        
                                                        
                                -----------  ---------- 
    Total liabilities and                               
     shareholders' equity        $3,796,464  $2,885,323 
                                ===========  ========== 












  QIAGEN N.V.                                                                                         
  RECONCILIATION OF REPORTED TO ADJUSTED FIGURES                                                      
  (unaudited)                                                                                         
                                                                                                      
  Three months ended December 31, 2009                                                                
  (in millions, except EPS data)                                                                      
                                                                                                      
                                                                                                      
                                         Net     Gross   Operating  Pre-tax   Income   Net    Diluted 
                                        Sales    Profit   Income     Income    Tax    Income   EPS*   
                                       -------  -------  ---------  -------  -------  ------  ------- 
  Reported results                      $289.1   $188.1      $42.9    $49.4   $(4.9)   $44.5    $0.18 
  Adjustments:                                                                                        
   Business integration, acquisition                                                                  
    related and restructuring costs         --      4.2       17.9     17.9    (6.3)    11.6     0.05 
   Purchased intangibles amortization       --     14.3       20.2     20.2    (7.5)    12.7     0.05 
   Share-based compensation                 --      0.1        2.4      2.4    (0.7)     1.7     0.01 
   Income from Divestitures and other                                                                 
    acquisition related income              --       --         --   (10.5)    (2.4)  (12.9)   (0.05) 
                                       -------  -------  ---------  -------  -------  ------  ------- 
                                                                                                      
   Total adjustments                        --     18.6       40.5     30.0   (16.9)    13.1     0.06 
                                       -------  -------  ---------  -------  -------  ------  ------- 
                                                                                                      
  Adjusted results                      $289.1   $206.7      $83.4    $79.4  $(21.8)   $57.6    $0.24 
                                       =======  =======  =========  =======  =======  ======  ======= 
                                                                                                      
  *Using 241 Mio. diluted shares                                                                      








  Three months ended December 31, 2008                                                                
  (in millions, except EPS data)                                                                      
                                                                                                      
                                                                                                      
                                         Net     Gross   Operating  Pre-tax   Income   Net    Diluted 
                                        Sales    Profit   Income     Income    Tax    Income   EPS*   
                                       -------  -------  ---------  -------  -------  ------  ------- 
  Reported results                      $237.2   $157.5      $40.4    $36.2  $(11.5)   $24.7    $0.12 
  Adjustments:                                                                                        
   Business integration, acquisition                                                                  
    related and restructuring costs         --      1.0        5.8      5.8    (1.4)     4.4     0.03 
   Purchased in-process R&D                 --       --        0.2      0.2       --     0.2       -- 
   Purchased intangibles amortization       --     13.2       17.1     17.1    (4.9)    12.2     0.06 
                                                                                                      
   Share-based compensation                 --      0.2        3.1      3.1    (0.9)     2.2     0.01 
                                       -------  -------  ---------  -------  -------  ------  ------- 
                                                                                                      
   Total adjustments                        --     14.4       26.2     26.2    (7.2)    19.0     0.10 
                                       -------  -------  ---------  -------  -------  ------  ------- 
                                                                                                      
  Adjusted results                      $237.2   $171.9      $66.6    $62.4  $(18.7)   $43.7    $0.22 
                                       =======  =======  =========  =======  =======  ======  ======= 
                                                                                                      
  *Using 202 Mio. diluted shares                                                                      








  QIAGEN N.V.                                                                                            
  RECONCILIATION OF REPORTED TO ADJUSTED FIGURES                                                         
  (unaudited)                                                                                            
                                                                                                         
  Twelve months ended December 31, 2009                                                                  
  (in millions, except EPS data)                                                                         
                                                                                                         
                                                                                                         
                                                   Gross   Operating  Pre-tax   Income    Net    Diluted 
                                       Net Sales   Profit   Income     Income    Tax     Income   EPS*   
                                       ---------  -------  ---------  -------  -------  -------  ------- 
  Reported results                      $1,009.8   $667.1     $180.2   $172.3  $(34.5)   $137.8    $0.64 
  Adjustments:                                                                                           
   Business integration, acquisition                                                                     
    related and restructuring costs           --      7.4       34.4     34.4   (11.3)     23.1     0.11 
   Purchased intangibles amortization         --     53.6       71.8     71.8   (25.6)     46.2     0.22 
   Share-based compensation                   --      0.8        9.7      9.7    (2.9)      6.8     0.03 
   Income from Divestitures and other                                                                    
    acquisition related income                --       --         --   (12.9)    (3.2)   (16.1)   (0.08) 
   Acquisition related write-off of                                                                      
    prepaid expenses and other asset                                                                     
    impairment                                --       --         --      2.7    (0.9)      1.8     0.01 
                                       ---------  -------  ---------  -------  -------  -------  ------- 
                                                                                                         
   Total adjustments                          --     61.8      115.9    105.7   (43.9)     61.8     0.29 
                                       ---------  -------  ---------  -------  -------  -------  ------- 
                                                                                                         
  Adjusted results                      $1,009.8   $728.9     $296.1   $278.0  $(78.4)   $199.6    $0.93 
                                       =========  =======  =========  =======  =======  =======  ======= 
                                                                                                         
  *Using 214 Mio. diluted shares                                                                         








  Twelve months ended December 31, 2008                                                                
  (in millions, except EPS data)                                                                       
                                                                                                       
                                                                                                       
                                         Net     Gross   Operating  Pre-tax   Income    Net    Diluted 
                                        Sales    Profit   Income     Income    Tax     Income   EPS*   
                                       -------  -------  ---------  -------  -------  -------  ------- 
  Reported results                      $893.0   $599.7     $145.7   $119.3  $(29.8)    $89.0    $0.44 
  Adjustments:                                                                                         
   Business integration, acquisition                                                                   
    related and restructuring costs         --      1.4       33.5     33.5   (11.2)     22.3     0.11 
   Purchased in-process R&D                 --       --        1.0      1.0       --      1.0     0.01 
   Purchased intangibles amortization       --     48.7       63.1     63.1   (21.1)     42.0     0.20 
   Share-based compensation                 --      1.0        9.4      9.4    (2.9)      6.5     0.03 
                                                                                                       
   Acquisition related impairment           --       --         --      4.0    (1.5)      2.5     0.01 
                                       -------  -------  ---------  -------  -------  -------  ------- 
                                                                                                       
   Total adjustments                        --     51.1      107.0    111.0   (36.7)     74.3     0.36 
                                       -------  -------  ---------  -------  -------  -------  ------- 
                                                                                                       
  Adjusted results                      $893.0   $650.8     $252.7   $230.3  $(66.5)   $163.3    $0.80 
                                       =======  =======  =========  =======  =======  =======  ======= 
                                                                                                       
  *Using 205 Mio. diluted shares                                                                       




CONTACT:  QIAGEN N.V.
          Roland Sackers, Chief Financial Officer
            roland.sackers@qiagen.com
          Dr. Solveigh Mahler, Director Investor Relations
            +49 2103 29 11710
            solveigh.maehler@qiagen.com
          Albert F. Fleury, Associate Director Investor Relations 
           North America
            +1 301 944 7028
            albert.fleury@qiagen.com


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